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Zepbound® for Weight Loss: What You Need to Know

What is Zepbound®?

Zepbound® (tirzepatide) is a new, once-a-week, FDA-approved weight loss injection designed for adults struggling with obesity or other weight-related health conditions like high blood pressure and type 2 diabetes.

$100 Off First Consultation

How does Zepbound® Work

Zepbound® mimics two natural hormones:

  • GLP-1 (Glucagon-Like Peptide-1)
  • GIP (Glucose-Dependent Insulinotropic Polypeptide)

Both of these hormones are released naturally by the gut after eating and play a significant role in:

Hunger Control

Zepbound® works by helping to control hunger, so you’re not constantly battling cravings. By targeting both GLP-1 and GIP receptors, it helps you feel fuller for longer, making it easier to stick to healthy eating habits and avoid overeating.
Blood Sugar Regulation

Zepbound® also helps keep your blood sugar levels in check. Improving your body’s insulin response it makes managing blood sugar smoother, which can be especially helpful if you’re looking to stabilize your energy levels or manage conditions like type 2 diabetes.
Fat Loss

If weight loss is your goal, Zepbound® can help by promoting fat metabolism. By reducing hunger and improving insulin balance, it supports your body in burning fat more effectively, helping you achieve your fitness goals.

Benefits of Zepbound®

Significant Weight Loss

Zepbound® has shown some of the most dramatic weight loss results of any medication on the market. In clinical trials, participants lost up to 22.5% of their body weight—nearly 48 pounds on average at the highest dose (15 mg). It’s not just a few pounds—this transformative weight loss rivals bariatric surgery for some individuals

Curb Cravings

Unlike other medications that work on just GLP-1, Zepbound® works on both GLP-1 and GIP receptors. This means more powerful appetite suppression and better energy storage and use regulation. Most people report feeling full faster, staying full longer, and having fewer cravings—even for high-calorie or sugary foods.

Respond Better to Sugar

Zepbound® helps your body use insulin more effectively, which can be life-changing for people with insulin resistance, prediabetes, or type 2 diabetes. Even those without diabetes see more stable energy, fewer blood sugar crashes, and easier weight loss, especially in areas like belly fat, which is linked to metabolic issues.

Long-Lasting, Sustainable Results

Because Zepbound® gradually reprograms hunger cues and boosts satiety, it supports long-term behavior change. Unlike crash diets or quick fixes, it helps create sustainable habits. Most people find they naturally eat smaller portions, make healthier choices, and feel more in control around food.

Convenient, Once-Weekly Dosing

Life is busy—Zepbound® fits in easily. It requires one injection, once per week, with a small, easy-to-use pen. There are no daily pills or multiple doses—just consistency, once a week.

Support for Your Heart and Metabolism

Beyond weight loss, Zepbound® supports your overall health by improving key markers of cardiovascular and metabolic wellness. It’s not just about looking better—it’s about reducing the risk of serious health conditions and helping your body function at its best. Zepbound supports overall health by improving:

  • Blood Pressure
  • LDL (Bad) Cholesterol
  • Triglyceride levels
Significant Weight Loss
Curb Cravings
Respond Better to Sugar
Support for Your Heart and Metabolism
Long-Lasting, Sustainable Results
Convenient, Once-Weekly Dosing

How to Take Zepbound®

  • Zepbound® is injected once a week (in the stomach, thigh, or upper arm).
  • The dose starts low (2.5 mg) and slowly increases over several weeks to help your body adjust and minimize side effects.
  • The full dose is 15 mg weekly, depending on your doctor’s guidance.

Who is a Good Fit?

Zepbound® is approved for adults who:

  • Have a BMI of 30 or higher
  • Have a BMI of 27 or higher with at least one weight-related condition (like high blood pressure, high cholesterol, or type 2 diabetes)

Who Should Avoid It?

Zepbound® isn’t recommended if you:

  • Have a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia type 2
  • Are pregnant or breastfeeding
  • Have severe gastrointestinal disease

Who is a Good Fit?

The most common side effects are GI-related and tend to improve over time:

  • Nausea
  • Diarrhea
  • Vomiting
  • Constipation
  • Bloating
peptide for weight loss

How do I get started with Zepbound® at Lowcountry Male?

Getting started with Zepbound® at Lowcountry Male begins with a personalized consultation with our experienced healthcare team. We’ll evaluate your health, discuss your weight loss goals, and design a customized treatment plan just for you. Our providers will ensure your treatment is safe and effective by determining the right dosage and monitoring your progress closely throughout your journey.

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Zepbound® Frequently Asked Questions (FAQs)

How quickly can I expect to lose weight on Zepbound®?
Most people start noticing changes in appetite within the first few weeks. Meaningful weight loss typically begins within the first month or two and continues steadily over time. The best results are usually seen after 6–12 months of consistent use.
Can I take Zepbound® if I don’t have diabetes?
Yes! Zepbound® is specifically approved for people who are overweight or obese—with or without diabetes. In fact, one of its biggest clinical trials focused on people without diabetes.
How is Zepbound® different from Ozempic® or Wegovy®?
Ozempic® and Wegovy® both use Semaglutide/GLP-1, which targets just one hormone (GLP-1). Zepbound® targets two hormones (GLP-1 and GIP), and studies have shown it can lead to even more weight loss and better hunger control compared to Semaglutide/GLP-1 alone.
What happens if I stop taking Zepbound®?

Like most weight loss medications, if you stop using it and return to old habits, weight may come back. That’s why it’s important to combine Zepbound® with healthy lifestyle habits like balanced eating, movement, stress management, and sleep. Think of it as a long-term tool, not a quick fix.

Do I need to follow a specific diet while on Zepbound®?

There’s no “one” diet required, but eating smaller, balanced meals can help minimize side effects and boost results. Most providers recommend a high-protein, low-processed-carb approach. Listen to your body—many people naturally eat less and crave healthier foods while on medication.

How to Get Zepbound® with Lowcountry Male.

At Lowcountry Male, we offer Zepbound® through our prescription partner, Lilly. While we don’t directly provide the medication, we will manage the prescription process and order it on your behalf. Our $150 fee covers the medication dosing, provider communication, and weight loss counseling. Lilly will charge $499 for a 1-month supply, billed separately.

Interested in learning if Zepbound® is right for you? Request an appointment with us below!

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